*These products also include praziquantel, an active ingredient that specifically controls tapeworms (Anoplocephala perfoliata)
Based on the largest survey of equine dewormer resistance reported to date. Forty-four farms/stables in five states.2
Strategic deworming instead of a blanket one-size-fits-all approach.
Count on your veterinarian’s expertise.Talk to your veterinarian about a customized deworming program for the horses in your stable.
1Barger IA and Lisle KA. Benzimidazole resistance in strongyles of horses. Aust Vet J 1979;55:594-595.
2Kaplan RM, et al. Prevalence of anthelmintic-resistant cyathostomes on horse farms. JAVMA 2004;225(6):903-910.
3Lyons ET, Tolliver SC, Ionita M, Collins SS. Evaluation of parasiticidal activity of fenbendazole, ivermectin, oxibendazole and pyrantel pamoate in horse foals with emphasis on ascarids (Parascaris equorum) in field studies on five farms in central Kentucky in 2007. Parasitol Res 2008;103:287-291.
4Woods TF, Lane TS, Zeng QY, Courtney CH. Anthelmintic resistance on pleasure horse farms in north-central Florida. In: Proceedings 42nd Annual Meeting of the AAVP. 1997:88.
5Kaplan RM, Hodgkinson JE, Thamsborg SM, Nielsen MK. Background and goals. In: Kaplan RM, Nielsen MK, eds. Proceedings of the Equine Parasite Drug Resistance Workshop 2008:3.
6Lyons ET, Tolliver SC, Collins SS. Probable reason why small strongyle EPG counts are returning “early” after ivermectin treatment of horses on a farm in central Kentucky. Parasitol Res 2009;104:569-574.
7Shoop WL, Haines HW, Michael BF, Eary CH. Mutual resistance to avermectins and milbemycins: oral activity of ivermectin and moxidectin against ivermectin-resistant and susceptible nematodes. The Veterinary Record 1993;133:445-447.
8Conder GA, Thompson DP, Johnson SS. Demonstration of co-resistance of Haemonchus contortus to ivermectin and moxidectin. The Veterinary Record 1993;132:651-652.
9Le Jambre LF, Gill JH, Lenane IJ, Lacey E. Characterization of an avermectin-resistant strain of Australian Haemonchus contortus. International Journal for Parasitology 1995;25:691-698.
10Sangster NC, Dobson RJ. Anthelmintic resistance. In: Lee DL, ed. The Biology of Nematodes. London: Taylor & Francis, 2002:531-567.
11Uhlinger CA, Kristula M. Effects of alternation of drug classes on the development of oxibendazole resistance in a herd of horses. J Am Vet Med Assoc 1992;201:51-55.
12Reinemeyer CR. Rational approaches to equine parasite control. Equine Parasite Control Kentucky Equine Research, Inc. 64-72.
13Kaplan RM. These ain’t your father’s parasites: An evidence-based medical approach to equine parasite control. The Practitioner October 2008.
14Kaplan R. Recommendation for standardization of fecal egg count reduction tests in cattle. AAVP 2007. Washington, D.C. Abstract 78:84-85.
15Brazik EL, et al. Pyrantel pamoate resistance in horses receiving daily administration of pyrantel tartrate. JAVMA 2006;228:101-103.
16Clayton HM. Ascarids: recent advances. In: The Veterinary Clinics of North America: Equine Practice. Philadelphia, Pa.; 1986;2(2):313-328.
17Merck Veterinary Manual, Ninth edition, 2005:268-269.
18Reinemeyer CR. Update on equine tapeworms presentation notes. Louisiana Veterinary Medical Association Equine Committee. September 21-23, 2003.
19Based on data provided in FDA Freedom of Information summaries.
20Based on data provided on the ZIMECTERIN Gold product label.
21Reinemeyer CR, et al. A prevalence survey of antibodies to Anoplocephala perfoliata in horses from the United States. Proc WAAVP 2003:18.
IMPORTANT SAFETY INFORMATION
ZIMECTERIN GoldWarning: Not for use in humans. Keep this and all drugs out of reach of children. In horses there have been rare reports of swelling and irritation of the mouth, lips and tongue following administration of ZIMECTERIN Gold. These reactions have been transitory in nature. Do not use in other animal species as severe adverse reactions, including fatalities in dogs, may result.
ZIMECTERIN Paste 1.87%Warning: Not for use in humans. Keep this and all drugs out of reach of children. Do not use in other animal species as severe adverse reactions, including fatalities in dogs, may result.